Nur’aini Safitri, - (2020) PENGARUH PEMBERIAN STINGLESS BEE HONEY DAN ENDURANCE TRAINING TERHADAP KADAR GULA DARAH, PENANDA PRO-INFLAMASI IL6 DAN TNF-ALPHA PADA OTOT SKELET TIKUS WISTAR. S2 thesis, Universitas Pendidikan Indonesia.
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Abstract
Tujuan penelitian ini untuk mengetahui pengaruh pemberian stingless bee honey dan endurance training terhadap kadar gula darah, pro-inflamasi IL-6 dan TNF-α pada otot skelet tikus wistar. Metode penelitian adalah True Eksperimental dengan desain The Randomize Posttest-Only Control Group Design. Populasi pada penelitian ini adalah tikus wistar jantan, dengan Teknik sampling yang digunakan adalah total sampling. Instrumen yang digunakan dalam penelitian ini adalah blood sampling (blood glucose autocheck) untuk mengukur kadar gula darah, dan instrumen western blot untuk melihat ekspresi protein pro-inflamasi IL6 dan TNF-α. Hasil penelitian menunjukkan bahwa : (1) Tidak terdapat pengaruh yang signifikan dari pemberian stingless bee honey terhadap kadar gula darah. (2) Terdapat pengaruh yang signifikan dari pemberian stingless bee honey terhadap parameter pro-inflamasi. (3) Terdapat pengaruh yang signifikan dari endurance training terhadap kadar gula darah. (4) Terdapat pengaruh yang signifikan dari endurance training terhadap parameter pro-inflamasi IL-6 dan TNF–α. (5) Terdapat pengaruh yang signifikan dari pemberian stingless bee honey dan endurance training terhadap kadar gula darah. (6) Terdapat pengaruh yang signifikan dari pemberian stingless bee honey dan endurance training terhadap parameter pro-inflamasi IL-6 dan TNF-alpha. The aim of this study was to enhance the effects of stingless bee honey and endurance training on blood glucose, pro-inflammatory IL-6 and TNF-a in Wistar rats skeletal muscle. The research method used a True Experimental with The Randomize Posttest-Only Control Group Design. The population in this study were male Wistar rats, the sampling technique was used total sampling. The instruments are used blood sampling (blood glucose autocheck) to measure blood glucose levels, and western blot instruments to see the expression of pro-inflammatory proteins IL6 and TNF α. The results showed that: (1) There is no significant effect of giving stingless bee honey on blood sugar levels. (2) There is a significant effect of stingless bee honey on pro-inflammatory parameters. (3) There is a significant effect of endurance training on blood sugar levels. (4) There is a significant effect of endurance training on the pro-inflammatory parameters of IL-6 and TNF-a. (5) There is a significant effect of stingless bee honey and endurance training on blood sugar levels. (6) There is a significant effect of stingless bee honey and endurance training on pro-inflammatory parameters of IL-6 and TNF-a.
| Item Type: | Thesis (S2) |
|---|---|
| Uncontrolled Keywords: | Stingless Bee Honey, Endurance Training, Inflammation, Blood Glucose, Rats. |
| Subjects: | L Education > L Education (General) S Agriculture > SK Hunting sports |
| Divisions: | Sekolah Pasca Sarjana > Pendidikan Olahraga S-2 |
| Depositing User: | Nur'aini Safitri |
| Date Deposited: | 19 Jan 2021 06:16 |
| Last Modified: | 19 Jan 2021 06:16 |
| URI: | http://repository.upi.edu/id/eprint/58343 |
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