Rachmayati, Fitria (2015) Pengaruh Ekstrak Temulawak (Curcuma Xanthorrhiza) Terhadap Aspek Reproduksi Mencit (Mus Musculus) Swiss Webster Jantan. S1 thesis, Universitas Pendidikan Indonesia.
|
Text
S_BIO_1104780_Title.pdf Download (153kB) | Preview |
|
|
Text
S_BIO_1104780_Abstract.pdf Download (140kB) | Preview |
|
|
Text
S_BIO_1104780_Table_of_content.pdf Download (250kB) | Preview |
|
|
Text
S_BIO_1104780_Chapter1.pdf Download (228kB) | Preview |
|
![[img]](http://repository.upi.edu/style/images/fileicons/text.png) |
Text
S_BIO_1104780_Chapter2.pdf Restricted to Staf Perpustakaan Download (368kB) |
|
|
Text
S_BIO_1104780_Chapter3.pdf Download (329kB) | Preview |
|
|
Text
S_BIO_1104780_Chapter4.pdf Restricted to Staf Perpustakaan Download (677kB) |
|
|
Text
S_BIO_1104780_Chapter5.pdf Download (135kB) | Preview |
|
|
Text
S_BIO_1104780_Bibliography.pdf Download (316kB) | Preview |
Abstract
Keterbatasan sumber daya alam dan pertambahan penduduk yang pesat merupakan masalah negara-negara yang sedang berkembang, termasuk Indonesia. Untuk menanggulangi masalah tersebut, pemerintah mengeluarkan program Keluarga Berencana guna menekan jumlah populasi penduduk. Rimpang temulawak (Curcuma xanthorrhiza) mengandung berbagai komponen kimia diantaranya kurkumin, protein, pati dan minyak atsiri yang diketahui dapat menurunkan proliferasi sel. Penelitian ini bertujuan untuk mengetahui efek pemberian ekstrak temulawak terhadap aspek reproduksi mencit (Mus musculus) jantan. Subjek penelitian ini adalah 24 ekor mencit jantan, dibagi menjadi 4 kelompok (Kontrol, 140 mg/kg BB, 280 mg/kg BB dan 700 mg/kg BB). Mencit diberi perlakuan secara gavage selama 30 hari setelah sebelumnya dilakukan aklimatisasi selama 7 hari. Sampel sperma diambil dari bagian epididimis mencit dan dilakukan pengujian jumlah, motilitas dan abnormalitas sperma. Sedangkan testis diambil untuk mendapatkan sayatan tubulus seminiferus dan mengukur berat testis. Data yang didapat dianalisis dengan uji Kruskal Wallis dan Mann Whitney (p<0,05) dengan taraf kepercayaan 95%. Hasil penelitian menunjukan bahwa pemberian ekstrak temulawak selama 30 hari berpengaruh signifikan terhadap penurunan berat testis, tetapi tidak berpengaruh signifikan terhadap jumlah sperma, motilitas, abnormalitas dan sayatan histologi testis. Limited natural resources and rapid population growth is a problem the countries that are developing, including Indonesian. To overcome these problems, the government issued a family planning program in order to reduce the number of population. Turmeric rhizome (Curcuma xanthorrhiza) containing various chemical components including curcumin, protein, starch and essential oils are known to degrade cell proliferation. This study aims to determine the effect of turmeric extract on reproductive aspects of mice (Mus musculus) male. The subjects were 24 male mice, were divided into 4 groups (control, 140 mg / kg, 280 mg / kg and 700 mg / kg). Mice were treated by gavage for 30 days after the previous acclimatization for 7 days. Samples taken from the epididymal sperm in mice and testing the number, motility and sperm abnormalities. While testicular taken to get the incision and measure the weight of the seminiferous tubules of the testes. The data obtained were analyzed with the Kruskal Wallis and Mann Whitney (p <0.05) with a 95% confidence level. The results showed that turmeric extract for 30 days significantly influence the decrease in testicular weight, but no significant effect on sperm count, motility, abnormalities and testicular histology incision.
| Item Type: | Thesis (S1) |
|---|---|
| Additional Information: | No. Panggil : S BIO RAC p-2015; Pembimbing : I. Didik Priyandoko, II. Hernawati |
| Uncontrolled Keywords: | Temulawak, Spermatozoa, Histologi Testis, Mencit |
| Subjects: | Q Science > QH Natural history > QH301 Biology |
| Divisions: | Fakultas Pendidikan Matematika dan Ilmu Pengetahuan Alam > Jurusan Pendidikan Biologi > Program Studi Pendidikan Biologi |
| Depositing User: | Staff DAM |
| Date Deposited: | 29 Oct 2015 04:47 |
| Last Modified: | 29 Oct 2015 04:47 |
| URI: | http://repository.upi.edu/id/eprint/18494 |
Actions (login required)
 |
View Item |