SINTESIS HIDROGEL CMC/CNC TANDAN KOSONG KELAPA SAWIT DAN APLIKASINYA DALAM PENGEMBANGAN SISTEM DETEKSI TEMPERATUR UNTUK MONITORING INFEKSI LUKA

    Aulia Umainah, - and Fitri Khoerunnisa, - and Swasmi Purwajanti, - (2025) SINTESIS HIDROGEL CMC/CNC TANDAN KOSONG KELAPA SAWIT DAN APLIKASINYA DALAM PENGEMBANGAN SISTEM DETEKSI TEMPERATUR UNTUK MONITORING INFEKSI LUKA. S1 thesis, Universitas Pendidikan Indonesia.

    Abstract

    ABSTRAK Peningkatan suhu pada area luka dapat menjadi indikator peradangan atau infeksi. Sensor temperatur dapat digunakan sebagai sistem deteksi dini peningkatan suhu lokal pada bagian infeksi luka, namun memerlukan support matrik yang bersifat biokompatibel dan termal konduktif. Penelitian ini bertujuan untuk mengembangkan hidrogel berbasis selulosa sebagai matrik support sensor suhu untuk deteksi dini infeksi luka. Hidrogel disintesis dengan metode sol-gel menggunakan karboksimetil selulosa (CMC) dari tandan kosong kelapa sawit (TKKS). dengan penambahan nanokristal selulosa (CNC) dan gliserol sebagai plasticizer dan antipembekuan. Pengaruh penambahan gliserol pada struktur, morfologi dan karakteristik fisiko-kimia, serta kinerja hidrogel sebagai support matrik sensor suhu dilakukan berbagai pengujian seperti FTIR, SEM, WCA, Swelling Ratio, dan UTM. Hasil penelitian menunjukkan bahwa komposisi optimum gliserol pada hidrogel komposit (CMC/CNC) diperoleh pada konsentrasi gliserol 4% (G-4/ 4%) dari uji kekuatan mekanik, WCA, dan penyerapan cairan (swelling ratio) yang baik. Penambahan gliserol memodifikasi struktur dan morfologi hidrogel akibat adanya peningkatan ikatan hidrogen antarmolekul dan menyebabkan peningkatan kerapatan matrik polimer. Hidrogel komposit memiliki kinerja yang baik sebagai support matrix sensor temperatur pada berbagai temperatur pengujian (36°C, 38°C, dan 40°C) memiliki respon cepat dan pembacaan suhu antara suhu sebenarnya dan suhu pada hidrogel relatif kecil, sesuai dengan rentang temperatur infeksi luka. Temuan ini menunjukkan hidrogel komposit potensial digunakan sebagai support matriks sensor suhu sebagai sistem deteksi infeksi luka. ABSTRACT An increase in temperature in the wound area can be an indicator of inflammation or infection. Temperature sensors can be used as an early detection system for local temperature increases in infected wounds, but they require a biocompatible and thermally conductive matrix support. This study aims to develop a cellulose-based hydrogel as a support matrix for temperature sensors for early detection of wound infections. The hydrogel was synthesized using the sol-gel method with carboxymethyl cellulose (CMC) from empty palm fruit bunches (EPFB). Nanocrystalline cellulose (CNC) and glycerol were added as plasticizers and antifreeze agents. The effect of glycerol addition on the structure, morphology, and physicochemical characteristics, as well as the performance of the hydrogel as a temperature sensor support matrix, was tested using various methods, such as FTIR, SEM, WCA, swelling ratio, and UTM. The results showed that the optimum glycerol composition in the composite hydrogel (CMC/CNC) was obtained at a glycerol concentration of 4% (G-4/4%) from mechanical strength, WCA, and liquid absorption (swelling ratio) tests. The addition of glycerol modified the structure and morphology of the hydrogel due to an increase in intermolecular hydrogen bonds, causing an increase in polymer matrix density. The composite hydrogel performed well as a temperature sensor support matrix at various test temperatures (36°C, 38°C, and 40°C), exhibiting a rapid response and a relatively small temperature reading difference between the actual temperature and the temperature on the hydrogel, which is in line with the temperature range of wound infection. These findings indicate that composite hydrogels have the potential to be used as a temperature sensor support matrix in wound infection detection systems.

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    Official URL: https://repository.upi.edu/
    Item Type: Thesis (S1)
    Additional Information: https://scholar.google.com/citations?user=VlUl5ZoAAAAJ&hl=en ID SINTA Dosen Pembimbing : Fitri Khoerunnisa: 258263
    Uncontrolled Keywords: Kata Kunci: hidrogel, CMC/CNC, gliserol, sensor temperatur, infeksi luka. Keywords: hidrogel, CMC/CNC, gliserol, temperatur sensor, wound infection.
    Subjects: Q Science > QD Chemistry
    Divisions: Fakultas Pendidikan Matematika dan Ilmu Pengetahuan Alam > Program Studi Kimia - S1 > Program Studi Kimia (non kependidikan)
    Depositing User: Aulia Umainah
    Date Deposited: 12 Sep 2025 08:41
    Last Modified: 12 Sep 2025 08:41
    URI: http://repository.upi.edu/id/eprint/138724

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