Farikha Diah Andini HP, - and Fitri Khoerunnisa, - and Hafiz Aji Aziz, - (2025) PENGEMBANGAN SENSOR SPCE BERBASIS MOLECULARLY IMPRINTED POLYMER KITOSAN UNTUK APLIKASI DETEKSI GLUKOSA DALAM URIN. S1 thesis, Universitas Pendidikan Indonesia.
Abstract
Diabetes Melitus (DM) merupakan penyakit jangka panjang akibat ketidakmampuan tubuh dalam mengatur kadar glukosa darah. Screen Printed Carbon Electrode/Molecularly Imprinted Polymer (SPCE/MIP) menjadi solusi alternatif sebagai perangkat sensing untuk deteksi keberadaan glukosa secara spesifik. Penelitian ini bertujuan untuk sintesis MIP berbasis kitosan dengan metode polimerisasi sol-gel, fabrikasi SPCE/MIP dengan metode drop casting, karakterisasi SPCE/MIP menggunakan instrumen UV-Vis, FTIR, dan SEM-EDX, dan uji kinerjanya sebagai sensor glukosa dalam urin menggunakan metode Electrochemical Impadance Spectroscopy (EIS). Hasil penelitian menunjukkan MIP berbasis kitosan berhasil disintesis dengan metode polimerisasi sol gel. Keberhasilan removal glukosa pada MIP penurunan nilai absorbansi UV-Vis, penurunan intensitas puncak khas serapan FTIR, serta citra SEM. Selain itu, kinerja nilai resistansi SPCE/MIP ditunjukkan berdasarkan nilai resistansi, nilai N CPE, Warburg Impedance yang mengindikasikan respon sensor. Nilai sensitivitas, linearitas, dan LOD dari SPCE/MIP masing-masing ditentukan berdasarkan plot impedansi berdasarkan metode EIS. Diabetes mellitus (DM) is a chronic disease caused by the body's inability to regulate blood glucose levels. Screen Printed Carbon Electrode/Molecularly Imprinted Polymer (SPCE/MIP) is an alternative solution as a sensing device for specific glucose detection. This study aims to synthesize chitosan-based MIP using the sol-gel polymerization method, fabricate SPCE/MIP using the drop casting method, characterize SPCE/MIP using UV-Vis, FTIR, and SEM-EDX instruments, and test its performance as a glucose sensor in urine using the Electrochemical Impedance Spectroscopy (EIS) method. The results showed that chitosan-based MIP was successfully synthesized using the sol-gel polymerization method. The success of glucose removal in MIP was indicated by a decrease in UV-Vis absorbance, a decrease in the intensity of the characteristic FTIR absorption peak, and SEM images. In addition, the performance of SPCE/MIP resistance was indicated by the resistance value, N CPE value, and Warburg Impedance, which indicated the sensor response. The sensitivity, linearity, and LOD values of the SPCE/MIP were determined based on impedance plots using the EIS method.
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| Item Type: | Thesis (S1) |
|---|---|
| Additional Information: | https://scholar.google.com/citations?hl=en&user=A2PSLxQAAAAJ https://scholar.google.com/citations?user=KwSBfPgAAAAJ&hl=en https://scholar.google.com/citations?user=R0Fi-UIAAAAJ&hl=en SINTA ID DOSEN PEMBIMBING Fitri Khoerunnisa: 258263 Hafiz Aji Aziz: 6748855 |
| Uncontrolled Keywords: | SPCE/MIP, sensor, glukosa, sol-gel, drop-casting SPCE/MIP, sensors, glucose, sol-gel, drop casting |
| Subjects: | Q Science > QD Chemistry R Medicine > R Medicine (General) T Technology > TP Chemical technology |
| Divisions: | Fakultas Pendidikan Matematika dan Ilmu Pengetahuan Alam > Program Studi Kimia - S1 > Program Studi Kimia (non kependidikan) |
| Depositing User: | Farikha Diah Andini HP |
| Date Deposited: | 17 Sep 2025 07:19 |
| Last Modified: | 17 Sep 2025 07:19 |
| URI: | http://repository.upi.edu/id/eprint/137936 |
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