Raden Muhamad Mukti Martadinata, - (2024) PENGARUH EKSTRAK TUMBUHAN KROKOT (Portulaca oleracea) TERHADAP KADAR GULA DARAH DAN BERAT BADAN MENCIT BETINA var. Swiss Webster. S1 thesis, Universitas Pendidikan Indonesia.
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Abstract
ABSTRAK Penelitian tentang pengaruh ekstrak tumbuhan krokot (Portulaca oleracea) terhadap kadar gula darah dan berat badan mencit betina var. swiss webster telah dilakukan. Tujuan penelitian ini untuk mendapatkan informasi mengenai pengaruh dan dosis signifikan terhadap penurunan kadar gula darah dan berat berat badan pada hewan uji. Rancangan Acak Lengkap (RAL) dengan lima kali pengulangan menggunakan perlakukan dosis: Dosis I (125 mg/kg BB), Dosis II (250 mg/kg BB), Dosis III (500 mg/kg BB) dan Kontrol positif (glibenklamid), Kontrol negatif dalam penelitian. Mencit betina usia dua bulan dengan rerata berat badan 25-35 g sebanyak 25 ekor diberi perlakuan ekstrak krokot dengan cara gavage selama 14 hari. Mencit diinduksi aloksan terlebih dahulu. Setelah itu dicek gula darah dan ditimbang pada hari ke 1, 7 dan 14. Hasil menunjukan ekstrak krokot dosis Dosis III (500 mg/kg BB) menurunkan gula darah pada hari ke-7 dan naik kembali pada hari ke-14. Sedangkan, Dosis II (250 mg/kg BB) signifikan menurunkan berat badan secara konstan hingga hari ke-14. Hasil penelitian dapat disimpulkan bahwa pemberian ekstrak krokot dapat berpengaruh menurunkan gula darah dan berat badan mencit. ABSTRACT Research on the effect of pursa (Portulaca oleracea) plant extract on blood sugar levels and body weight of female mice var. swiss webster has done. The aim of this research is to obtain information regarding the significant effects and doses on reducing blood sugar levels and body weight in test animals. Completely Randomized Design (CRD) with five repetitions using treatment doses: Dose I (125 mg/kg BB), Dose II (250 mg/kg BB), Dose III (500 mg/kg BB) and Positive control (glibenclamide), Negative control in study. Twenty-five two-month-old female mice with an average body weight of 25-35 g were treated with purslane extract by gavage for 14 days. Mice were induced with alloxan first. After that, blood sugar was checked and weighed on days 1, 7 and 14. The results showed that dose III of purslane extract (500 mg/kg BB) reduced blood sugar on day 7 and rose again on day 14. Meanwhile, Dose II (250 mg/kg BB) significantly reduced body weight consistently until the 14th day. The results of the research can be concluded that giving purslane extract can have an effect on reducing blood sugar and body weight in mice.
| Item Type: | Thesis (S1) |
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| Additional Information: | muhammadmukti823@upi.edu Saefudin Sinta.ID 6721267 |
| Uncontrolled Keywords: | Kadar gula darah, Berat badan, Krokot, Mencit. Blood sugar levels, body weight, purslane, mice. |
| Subjects: | Q Science > QK Botany R Medicine > RA Public aspects of medicine |
| Divisions: | Fakultas Pendidikan Matematika dan Ilmu Pengetahuan Alam > Jurusan Pendidikan Biologi > Program Studi Biologi (non kependidikan) |
| Depositing User: | Raden Muhamad Mukti Martadinata |
| Date Deposited: | 18 Sep 2024 06:36 |
| Last Modified: | 18 Sep 2024 06:36 |
| URI: | http://repository.upi.edu/id/eprint/125284 |
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